In accordance with the ACR classification, the EliA ANA screen correlates with alternative methods for detection and contains these antigens U1RNP (RNP 70, A, C), SSA/Ro (60 kDa, 52 kDa), SSB/La, Centromere B, Scl-70, Jo-1 proteins, and native purified Sm proteins. Assay results should be used in conjunction with clinical findings and other serological tests. Jo-1 antibodies can be found as markers in polymyositis, dermatomyositis and intestinal pneumonitis. Scl-70 antibodies are characteristic and specific for scleroderma. Do I have Lupus Positive ANA ANA test positive 1:80 ANA test positive 1:80 My 10 yr old is positive for ANA and positive DNA (DS) Ad, IgG Positive ANA but everything else is negative. CENP antibodies are found in patients with CREST Syndrome. Positive Ana-Lupus mononucleosis as a teen 20 year old and positive ANA as a woman in her mid 40s Lupus symptoms test negative positive ana with high titer. SS-B/La antibodies are highly specific clinical markers for Sjögren’s syndrome, but a small proportion of patients can remain SS-B/La negative. SS-A/Ro antibodies can be a marker for SLE and Sjögren’s syndrome. U1RNP antibodies in the absence of RNP 70 may indicate SLE. IMO, you would be smart to see a rheumatologist to check your sed rate (ESR), rheumatoid factor (RF), and look for more specific antibodies. Since youve been gluten-free for three years I doubt thats the cause of the positive test. RNP 70 antibodies are more specific for MCTD. ANA is a general term for autoantibodies (antibodies designed to destroy your own cells). U1-RNP antibodies are used to diagnosis SLE and mixed connective tissue disease (MCTD). Smith antibodies are highly specific, although insensitive, clinical markers for systemic lupus erythematosus (SLE). Antinuclear antibodies (ANA) are specific serological markers for the diagnosis and disease management of patients with connective tissue diseases (CTD).
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